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We are part of the MRC Protein Phosphorylation & Ubiquitylation Unit at the University of Dundee.
Our lab aims to understand the molecular mechanisms by which posttranslational modifications of proteins orchestrate cellular pathways to maintain homeostasis. We focus on the ubiquitin system, as the attachment of ubiquitin and ubiquitin-like proteins (UBLs) is fundamentally important in numerous cellular processes. By integrating structural, biochemical, proteomic, and cell biology approaches, we investigate how cells regulate protein synthesis, quality control, and degradation. Our work particularly explores the dynamic regulation of these pathways during cellular stress responses and their implications for human disease. |
Our Values
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Our lab is a diverse, multicultural and multinational environment with individuals from different parts of the world who have a rich variety of backgrounds and approaches to life. Our aim is to welcome all people to our lab, regardless of race, gender, social background or sexual preference. In our lab, we care deeply about integrity, inclusivity, diversity, team work and dedication. We promote these values and strive to uphold them in our daily life.
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Latest lab news
Alicia successfully defends her PhD thesis! A big thank you to Prof. Ron Hay (Dundee) and Dr. Paul Elliott (Oxford) for examining her thesis
Joshua Peter wins the 2023 Dundee Molecular and Cellular Biology Prize. Congrats Joshua! More details here
Congratulations Sven Lange, former lab member, being awarded a prestigious and highly competitive postdoctoral fellowship from The Charles A. King Trust to do his postdoctoral research at Harvard.
